Answer: It is an autosomal recessive genetic disorder characterized by an accumulation of copper in the liver and brain. The Wilson’s gene is ATP7B, which is either absent or markedly diminished in Wilson’s disease. The lack of the gene results in diminished synthesis of ceruloplasmin and/or defective transport of hepatocellular copper into bile for excretion. [...]

Answer: Viral hepatitides A,B,C,D,E Drugs: acetaminophen, antituberculosis drugs, troglitazone, Ectasy Herbal medications: Jin bu huan, comfrey Toxins: Amanita phalloides, carbontetrachloride, trichloroethyleneVascular: Budd-Chiari syndrome, veno-occlusive disease, ischemia or hypoxia, heatstroke Miscellaneous: malignant infiltration, Wilson’s disease, acute fatty liver of pregnancy, Reye’s syndrome Reference: Sleisenger MH, Fordtran JS (eds): Gastrointestinal Disease: Pathophysiology, Diagnosis, and Management, 7th ed. [...]