Health Questions and Answers

Archive for June, 2008

Question: Which chemotherapeutic agents are used in the treatment of squamous cell cancers of the head and neck? How effective are they?

Monday, June 30th, 2008

Answer: Effective agents include 5-fluorouracil (5-FU) infusions with cisplatin or carboplatin, taxanes, methotrexate, bleomycin, and mitomycin C. Response rates for these agents vary from 25% to 80%, depending on the agent, schedule, tumor type, previous treatment, and performance status. Combination chemotherapy regimens usually show higher initial response rates but have yet to show an increase […]

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Question: What is the most appropriate treatment of head and neck cancer?

Sunday, June 29th, 2008

Answer: Early-stage head and neck cancers are treated primarily with surgery, usually involving radical neck node dissection, sometimes accompanied by postoperative radiotherapy. Radiotherapy is also used for recurrences that are not amenable to surgery. Depending on tumor location and stage, some head and neck cancers are treated with multimodality therapy, using chemotherapy in combination with […]

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