Answer:
Dr. J.M. Tanner proposed a five-stage system to grade breast and pubic hair development in girls and genital and pubic hair development in boys.
TANNER STAGES OF PUBERTAL DEVELOPMENT IN GIRLS

Breast Development

Pubic Hair Development

Elevation of papilla only

No pubic hair

Breast budding

Scattered labial hair

Enlargement of breasts without
areola separation

Hair spreading to mons pubis

Slight lateral spread

Secondary mound formed by areola

Hair [...]

Answer:
No.  It appears that the HPG axis is intact as early as 20 weeks of life. Pituitary gonadotrophs have been found to produce LH and FSH at this gestational age, and in boys testicular testosterone is essential for normal internal and external genital development. In female fetuses, functional ovarian cysts are occasionally seen. These findings [...]

Answer:
Estrogen increases bone growth, especially in the axial skeleton. Growth hormone has more effect on the long bones. As a result of this, hypogonadal patients often have a short trunk as compared to their arm span and lower extremity length (eunichoid habitus). Growth hormone-deficient subjects often have the opposite appearance. Estrogen also promotes fusion of [...]

Answer:
The first sign of puberty is an increase in luteinizing hormone (LH) pulsatility at night. This pulsatility is followed by LH and follicle-stimulating hormone (FSH) pulses throughout the day, leading to increasing estrogen levels from the growing ovarian follicle, and finally positive feedback of estradiol to initiate an LH surge capable of inducing ovulation. Elevated [...]

Answer:
The first sign of puberty is often said to be breast budding (thelarche) around age 10. In fact, an increase in linear growth velocity can be appreciated 1-2 years prior to breast budding, heralding the onset of puberty. Thelarche is followed by pubic hair development (pubarche) at age 11, attainment of peak growth velocity (9 [...]

Answer:
Puberty is the developmental process by which fully competent adult reproductive capacity is established. It is characterized by marked neuroendocrine and physiologic changes in the reproductive system, culminating in mature secondary sexual characteristics and, in girls, the ability to ovulate and menstruate. Significant increases in somatic growth as well as dramatic psychosocial changes also characterize [...]