What is Barrett’s esophagus? Barrett’s esophagus is a metaplastic change in the lining of the normally squamous-lined esophagus that is recognized at endoscopy. As a result of gastroesophageal reflux disease, the esophagus is lined with intestinal metaplasia, a premalignant epithelium. How is Barrett’s esophagus diagnosed? The ultimate criterion for histologic diagnosis is the presence of [...]