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Archive for the 'Cancer Information' Category

What treatments are used for early chronic lymphocytic leukemia (CLL)?

Saturday, February 13th, 2010

CLL is the most common leukemia in the United States, and the incidence increases with age. Observation is generally chosen for patients in the early stages; alkylating agents and combination chemotherapy are offered to other selected patients. Reference: Hazzard WR, et al (eds): Principles of Geriatric Medicine and Gerontology, 5th ed. New York, McGraw-Hill, 2003

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When an older person is found to a have a monoclonal gammopathy of undetermined significance (MGUS), what are the chances of developing a related malignancy in the next 10 years?

Saturday, February 13th, 2010

A monoclonal gammopathy is a condition in which a monoclonal protein (M spike) is identified on serum protein electrophoresis of IgG < 3.5 g/dl or IgA < 2 gm/dL without associated signs or symptoms of a hematologic abnormality. At 10 years of follow-up, 40% of elderly patients diagnosed with MGUS are stable, 40% have died […]

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