Answer: Most types of tumors can metastasize to the lungs. Therefore, the more common the tumor, the more commonly it is found to have spread to the lung (e.g., breast cancers). Although they also can spread to the lungs, GI cancers tend to first metastasize locally and to the liver before pulmonary involvement is seen. [...]

Answer: Renal cell carcinoma and multiple myeloma tend to be purely lytic, prostate carcinoma tends to be mainly blastic, and the others are mixed. Tumors that are lytic are most often associated with hypercalcemia, whereas blastic metastases are not generally associated with this complication. Reference:  DeVita T Jr, Hellman S, Rosenberg SA (eds): Cancer: Principles [...]

Answer: Cancers of the lung, breast, kidney, prostate, and thyroid as well as multiple myeloma and malignant melanoma spread to bone most commonly. Reference: Casciato DA, Lowitz BB (eds): Manual of Clinical Oncology, 5th ed. Boston, Little, Brown, 2000.

Answer: Predisposing factors for infection include defects in cellular and humoral immunity, organ compromise due to tumor-related obstruction, chemotherapy-related granulocytopenia, disruption of mucosal (e.g., respiratory and alimentary tract) and integumental surfaces, iatrogenic procedures or placement of prosthetic devices, central nervous system dysfunction, and hyposplenic or postsplenectomy states. Reference:  Casciato DA, Lowitz BB (eds): Manual of [...]

Answer: Anemia in cancer patients is often multifactorial. Anemia may result from blood loss due to bleeding from tumors or from gastritis due to the use of nonsteroidal anti-inflammatory agents (NSAIDs). It may also be caused by hemolysis (secondary to antibodies associated with the tumor), disseminated intravascular coagulation (DIC), sepsis, or a paraneoplastic syndrome. Anemia [...]