Health Questions and Answers

Archive for the 'Hematology' Category

Question: How do diet and neurologic disease differ in vitamin B12 and folate deficiencies?

Wednesday, December 5th, 2007

Answer: Diet may be normal in vitamin B12 deficiency, but patients with folate deficiency may be alcoholics or have a diet consisting mainly of junk food and “tea and toast,” with no green vegetables. Neurologic disease in vitamin B12 deficiency is subacute and involves combined systems; in folate deficiency it is absent or associated with […]

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Question: What is chronic intravascular hemolysis?

Wednesday, December 5th, 2007

Answer: Chronic intravascular hemolysis is a disorder usually seen in paroxysmal nocturnal hemoglobinuria, a rare stem cell disorder, or in patients with malfunctioning cardiac valves. Examination of urine sediment stained for iron discloses iron-laden tubular cells (hemosiderosis). Reference: Greer JP, et al (eds): Wintrobe’s Clinical Hematology, 11th ed. Philadelphia, Lippincott Williams & Wilkins, 2004

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