Health Questions and Answers

Archive for the 'Rheumatology' Category

Question: How effective are the TNF inhibitors in the treatment of RA?

Wednesday, April 16th, 2008

Answer: The TNF inhibitors have shown dramatic efficacy in the treatment of RA. Careful studies have shown significant improvements in function, lessening the number of swollen and tender joints and a slowing of the radiographic progression of disease. These medications have been used safely and effectively with more traditional DMARDs as well. The most common […]

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Question: What are the newest options for treatment of RA?

Wednesday, April 16th, 2008

Answer: The newest options for the treatment of RA are anti-cytokine regimens. Three preparations (etanercept [Enbrel], infliximab [Remicade], and adalimunmab [Humira]) target TNF-α and one targets IL-1R (anakinra [Kineret]). All of these options are given parenterally and are fairly expensive. Anakinra, although proven efficacious, requires daily injections and has a slower onset of action and […]

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