Health Questions and Answers

Archive for the 'Systemic Lupus Erythematosus' Category

Question: Does lupus nephritis recur in a transplanted kidney?

Tuesday, May 6th, 2008

Answer: Disease activity in SLE often quiets with the onset of uremia and dialysis. Several studies note the ability to discontinue glucocorticoids without a return of extrarenal manifestations once dialysis has been initiated. Although there are reports of subsequent disease exacerbations, disease activity usually does not recur in transplanted kidneys. Reference: Koopman WJ (ed): Arthritis […]

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Question: What antibody is often touted to be diagnostic for drug-induced lupus?

Tuesday, May 6th, 2008

Answer: Although often touted to be diagnostic for drug-induced lupus, an antihistone antibody is not particularly helpful when a patient taking one of the above medications has features of lupus and a positive ANA. Although antihistone antibody is present in the syndrome of drug-induced lupus (perhaps as many as 90% of cases), it is also […]

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