Health Questions and Answers

Question: Does lupus nephritis recur in a transplanted kidney?

Answer:

Disease activity in SLE often quiets with the onset of uremia and dialysis. Several studies note the ability to discontinue glucocorticoids without a return of extrarenal manifestations once dialysis has been initiated. Although there are reports of subsequent disease exacerbations, disease activity usually does not recur in transplanted kidneys.

Reference: Koopman WJ (ed): Arthritis and Allied Conditions: A Textbook of Rheumatology, 15th ed. Philadelphia, Lippincott Williams & Wilkins, 2005.

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