http://www.randyamy.com Trustworthy, Credible, and Timely Health Information Mon, 03 Nov 2008 02:50:24 +0000 http://backend.userland.com/rss092 en Answer: Serology-IgG or IgA antibodies directed at various bacterial antigens can be detected by enzyme-linked immunosorbent assay (ELISA) in serum of infected individuals. In addition, several office-based serologic methods are commercially available. Serologic methods detect evidence of primary H. pylori infection in untreated people with sensitivity and specificity >90%. Although antibody ... http://www.randyamy.com/question-how-is-helicobacter-pylori-diagnosed-noninvasively Answer: Histopathologic examination is widely available, and specimens are easy to store. Organisms can be detected with standard hematoxylin and eosin stains or special stains, such as Giemsa or Warthin-Starry, which make the organisms easier to identify. The sensitivity and specificity of histopathology for H. pylori are greater than 95% but ... http://www.randyamy.com/diagnose-helicobacter-pylori-infection Answer: The organism generally does not directly invade the epithelial cells but indirectly makes the gastric mucosa more vulnerable to acid peptic damage by disrupting the mucous layer, liberating a variety of enzymes and toxins, and adhering to and altering the gastric epithelium. In addition, the host immune response to H. ... http://www.randyamy.com/question-how-does-helicobacter-pylori-produce-mucosal-damage Answer: The organism lives within or beneath the gastric mucous layer, somewhat protected from stomach acid. H. pylori has potent urease activity, which hydrolyzes urea to ammonia and bicarbonate and increases its resistance to the stomach's low pH environment. H. pylori recognizes and binds to specific receptors expressed by gastric epithelial ... http://www.randyamy.com/question-where-in-the-gastrointestinal-gi-tract-does-helicobacter-pylori-live Answer: H. pylori is a spiral-shaped, gram-negative bacterium, 0.5 microns in width and 2-6.5 microns in length. It is distinguished by its multiple sheathed, unipolar flagella and potent urease activity; urease accounts for more than 1% of the organism's protein weight. Its shape and flagella allow penetration of and movement through ... http://www.randyamy.com/question-why-is-helicobacter-pylori-a-unique-bacterium Answer: Patients chronically infected with H. pylori frequently develop gastric and duodenal ulcer disease, especially the latter. Although less common, B-cell lymphoma and adenocarcinoma of the stomach are also associated with chronic gastritis due to H. pylori. Antral-predominant corpus sparing chronic gastritis due to H. pylori is more often associated with ... http://www.randyamy.com/question-what-are-the-long-term-implications-of-helicobacter-pylori-infection Answer: Lymphocytic gastritis (LG) is a special form of gastritis, which is characterized by the accumulation of intraepithelial lymphocytes (IELs) containing cytotoxic granules in the surface and foveolar epithelium. The number of IELs in normal gastric mucosa is between 3 and 8 per 100 epithelial cells; a minimal number of 30 ... http://www.randyamy.com/question-describe-lymphocytic-gastritis