Yes. Glucagon given intravenously may be effective in meat impactions of the lower esophagus. Glucagon acts by relaxing the lower esophageal sphincter. It does not appear to be effective in upper-or mid esophageal foreign bodies. It also does not affect peristalsis once the sphincter is relaxed. The weight of the object itself or the barium ( if a barium study is done) along with normal peristalsis pushes the foreign body through the esophageal sphincter. Papain and other “digestive agents,” on the other hand, should not be used.