Health Questions and Answers

Question: What medications are used for the treatment of obesity?

Answer:

Phentermine, a norepinephrine agonist (15-30 mg/day)
Sibutramine, a combination norepinephrine/serotonin reuptake blocker (5, 10, and 15 mg; start with 10 mg and titrate)
Orlistat, a pancreatic lipase inhibitor (120 mg 3 times/day before meals)

Reference: Larson PR, et al: Williams Textbook of Endocrinology, 10th ed. Philadelphia, W.B. Saunders, 2003.

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