Health Questions and Answers

Question: Are antimalarial agents useful as DMARDs?

Answer:

Hydroxychloroquine (Plaquenil) is pretty well the uniquely used antimalarial medication in the U.S. (over chloroquine [Aralen] and quinacrine [Atabrine]). Antimalarial medications are believed to be weak, have a slow onset of action, and are generally used in mild disease or in combination with other DMARDs.

Reference: Hochberg MC (ed). Rheumatology, 3rd ed. St. Louis, Mosby, 2003

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