Health Questions and Answers

Question: Do nausea and vomiting in pregnancy have fetal complications?


Both NVP and HG have been associated with a decreased risk of spontaneous abortion in the first and second trimesters. In terms of adverse outcome, there does not appear to be any significant risk of intrauterine growth restriction (IUGR) or stillbirth with mild to moderate symptoms. The literature on severe disease is mixed. In one study, 32% of infants born to mothers with weight loss in pregnancy had weights < 10% for gestational age at birth, compared to 6% inci dence of IUGR in mothers with nausea and vomiting without weight loss. Other authors have not confirmed this risk, and the issue remains controversial. There does not, however, seem to be any increased risk of congenital anomalies with HG.

Reference: Creasy RK, Resnik R: Maternal Fetal Medicine, 4th ed. Philadelphia, WB Saunders, 1999, pp 122-131.

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