Answer:

Numerous interventions have been attempted. Dietary manipulation, with decreased sodium intake or increased calcium intake, and pharmacologic therapy, with prophylactic low-dose aspirin, have been extensively studied with randomized controlled trials. Unfortunately, neither of these interventions has been able to reduce the incidence of preeclampsia.

Reference: American College of Obstetricians and Gynecologists: Diagnosis and Management of Preeclampsia and Eclampsia. ACOG Practice Bulletin No. 33. Obstet Gynecol 99:159-167, 2002.

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