Health Questions and Answers

Question: What are the major sites of calcium resorption in the nephron?


About 50% of the filtered calcium is reabsorbed in the proximal tubule, and most of the remainder (about 40% of the total) is reabsorbed in the loop of Henle, primarily the ascending limb of the loop of Henle. A small amount of calcium is reabsorbed in the distal convoluted tubule and an even smaller amount in the collecting tubule.

Reference: Brenner RM (ed): Brenner & Rector’s The Kidney, 7th ed. Philadelphia, W.B. Saunders, 2004

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