Health Questions and Answers

Question: What are the symptoms of intracranial metastases?

Answer:

Headache occurs in up to 50% of patients with intracranial metastases. It is classically described as occurring early in the morning, disappearing or decreasing after arising, and may be associated with nausea and/or projectile vomiting. Other symptoms include focal signs such as unilateral weakness, numbness, seizures, or cranial nerve abnormalities. Nonfocal complaints such as mental status changes or ataxia may occur.

Reference:  Calabresi P, Schein PS (eds): Basic Principles and Clinical Management of Cancer, 2nd ed. New York, Macmillan, 1993.

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