Health Questions and Answers

Question: What is chronic intravascular hemolysis?

Answer:

Chronic intravascular hemolysis is a disorder usually seen in paroxysmal nocturnal hemoglobinuria, a rare stem cell disorder, or in patients with malfunctioning cardiac valves. Examination of urine sediment stained for iron discloses iron-laden tubular cells (hemosiderosis).

Reference: Greer JP, et al (eds): Wintrobe’s Clinical Hematology, 11th ed. Philadelphia, Lippincott Williams & Wilkins, 2004

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