Health Questions and Answers

Question: What percent of patients with primary Sjögren’s syndrome subsequently develop a connective tissue syndrome?

Answer:

If symptoms of an underlying connective tissue disease do not appear within 12 months of the keratoconjunctivitis sicca, the chances are approximately 10% that it will appear later in life.

Reference: Talal N: Sjögren’s syndrome and connective tissue diseases association with other immunologic disorders. In McCarty DJ, Koopman WJ (eds): Arthritis and Allied Conditions, 12th ed. Philadelphia, Lea & Febiger, 1993

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