Health Questions and Answers

Question: What prophylactic regimens are recommended for traveler’s diarrhea?


  • Ciprofloxacin, 500 mg twice daily for 5 days (or one of the other fluoroquinolones)
  • Bismuth subsalicyate (Pepto-Bismol), 2 tablets with every meal and at bedtime for 5 days
  • Bactrim DS, one tablet twice daily for 3 days (Note: Many organisms are now resistant to Bactrim.)

Reference: Sleisenger MH, Fordtran JS (eds): Gastrointestinal Disease: Pathophysiology, Diagnosis, and Management, 7th ed. Philadelphia, W.B. Saunders, 2003

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