Health Questions and Answers

Question: Which tumors metastasize to the lungs?

Answer:

Most types of tumors can metastasize to the lungs. Therefore, the more common the tumor, the more commonly it is found to have spread to the lung (e.g., breast cancers). Although they also can spread to the lungs, GI cancers tend to first metastasize locally and to the liver before pulmonary involvement is seen. Tumors that spread via the bloodstream, such as sarcomas, renal cell carcinoma, and colon cancer, tend to produce nodular lung lesions. Those that spread via lymphatic routes, such as cancers of the breast, pancreas, stomach, and liver, often manifest a pattern of lymphangitic spread.

Reference:  Calabresi P, Schein PS (eds): Basic Principles and Clinical Management of Cancer, 2nd ed. New York, Macmillan, 1993

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