Answer:

Lipoproteins are named based on their density and are composed of nonpolar (and therefore water-insoluble) cholesterol esters and triglycerides surrounded by a layer of polar (and therefore water-soluble) proteins and lipids (unesterified cholesterol and phospholipids). This structure allows the entire particle to remain miscible in serum.

LIPOPROTEIN PARTICLES

Lipoprotein Particle	Location of Origin	Composition	Apoproteins	Associated Disorders
Chylomicron	Intestine	80-95% TG	Apo B48	Chylomicronemia
		3-7% chol
VLDL	Liver	50-65% TG	Apo B100	Familial hyper triglyceridemia
		20-30% chol
				Familial combined hyperlipidemia
Remnants and IDL	Catabolism ofVLDL & chylomicrons	30-40% TG 30-50% chol	Depends on particle of origin	Familial dysbeta-lipoproteinemia (Broad beta disease)
LDL	IDL, VLDL remnants	4-10% TG 45-55% chol	B-100	Familial hypercholesterolemia,
				Familial combined hyperlipidemia
HDL	Liver, intestine	3-7% TG 25% chol	Apo A	Tangier’s disease

VLDL = very low density particle, LDL = low-density particle, ID = intermediate density particle, HDL = high-density particle, TG = triglycerides, chol = cholesterol.

Reference: American Heart Association: www.americanheart.org

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